Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer
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Well, after doing a bunch of research and checking out the testimonials here and somewhere else, I chose to purchase Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer. Though I 'd have liked a much better warranty, I chose the functions were attractive enough to attempt it. It is a bunch of cash to toss away if it fails just after the guarantee. I am completely in love with this product. It is high quality item, clever features. I just got it today, and I will upgrade my review later if needed.
Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer Explanation
The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer Features
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Most Underlined Buyer Review : Compelling evidence to support cancer as a metabolic disease
Dr. Seyfried provides compelling evidence that cancer is a metabolic disease (NOT a genetic disease), and this has major implications for the treatment and prevention of cancer.
According to Otto Warburg's theory of cancer, mitochondrial dysfunction is the origin of cancer. Dr. Seyfried has amassed extensive evidence to support Warburg's theory and advances the idea that cancer arises from defects in energy metabolism (mitochondrial dysfunction), and that this metabolic dysfunction triggers genomic instability by activating oncogenes, inactivating tumor suppressor genes, etc. The author does an incredible job at convincing the reader that healthy mitochondria are the ultimate tumor suppressor.
It's clear that the strategy to treat cancer as a genetic disease is not working, but this fuels the pharmaceutical industry. Enormous amounts of money are spent on large cancer genome projects, but this has not advanced our understanding or treatment of cancer. The...
What Other Purchaser point out?
Iconoclastic approach to cancer
Dr. Seyfried has distilled a life time of basic science investigation into a brilliant summary of the causes of cancer. Although heavily scientific it reads like a mystery novel.
He directly challenges the prevalent "gene theory" of cancer that forms the basis of virtually all investigative efforts into cancer. He then details the origin, scientific basis and practicality of the metabolic cause of cancer.
Most importantly, he proposes a paradigm shift in how we should at least consider treating malignancies and in particular, brain cancer.
Based on evolutionary biology this book makes sense! It should be read by every scientist involved with the biology and treatment of cancer and by laymen with a scientific background. It is one of the most important books I have read as a neurosurgeon dealing with brain tumor patients in over 25 years.
a new look at caloric restriction and cancer
It has been known for a long time that caloric restriction led to longevity but also that it stopped cancer growth, some completely and many partial suppression with later recurrences.
Dr. Seyfried spent his whole career looking at an old concept defining cancer as a metabolic abnormality (Warburg). The fact that our PET scans show high glucose uptake in almost all types of cancer proves that cancers have a unique metabolic abnormality unlike normal differentiated cells. Simply put cancer cells require large amounts of glucose, or sugar to survival and multiply.
The cancer cells have an inefficient metabolism utilizing fermentation or glycolysis instead of using mitochondria for a more efficient way of make ATP energy via oxidative phosphorylation.
Why our own medical profession has not looked into this feature of cancer for therapeutic strategies is also odd.
It is well know that Caloric Restriction stops cancer growth and many nutritional...
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